Dendritic Imaging
Dendritic Imaging uses two-photon microscopy and targeted regional scanning to visualize fine neuronal structures and measure functional signals deep in the brain with high SNR and reduced motion artifacts.
About Dendritic Imaging
Dendrites and dendritic spines are characterized by fine, thin and elongated structures therefore they are difficult to study. However, using two-photon technology, we are able to detect signals from deeper regions of the brain, while avoiding phototoxicity. Additionally, spatially confined, regional scanning of axons, dendrites and spines allows detecting even subthreshold signals with high signal-to-noise ratio (SNR). We have several configurations aiding the visualization of dendritic arborization, and perform functional measurements in vivo and in vitro. Now, with the help of our new Femtonics 3D Real-Time Motion Correction, motion artifacts - even during in vivo dendritic measurements - will no longer be a problem!
3D Dendritic Imaging - FEMTO3D Atlas
With the FEMTO3D Atlas, point scanning speeds up to a 100kHz can be achieved, which helps determining activity at virtually any sites on dendrites. 3D random-access point scanning and its advanced versions support all kinds of functional dendritic imaging from single spine investigations to full arborization measurements, even combined with photostimulation solutions.
2D Dendritic Imaging - FEMTOSmart
FEMTOSmart offers numerous imaging opportunities and thanks to its modularity researchers can study dendrites with spines from wide variations of perspectives.
Key methods of Dendritic Imaging
3D Random-Access Point
3D Trajectory-Line
3D Ribbon
3D Snake
High-Speed Arbitrary Frame
2D Multiple-Line
Folded Frame
Dendritic Imaging scanning methods
Advance your research with Dendritic Imaging
Talk to an application specialist about your research, or book a demo at one of our facilities.