Voltage imaging

Voltage imaging

Resolve individual action potentials in vivo, including spikes within fast bursts, at the temporal resolution voltage signals demand.

About Voltage Imaging

Genetically encoded voltage indicators (ASAP, JEDI2P, etc.) have recently attained a level of quality that renders them valuable tools for studying membrane potentials throughout cells. However, a significant challenge has persisted: the lack of sufficiently fast equipment to capture their dynamics. Until now, there has been a shortage of systems capable of imaging at speeds exceeding kHz, approaching the electrophysiological standard of 10 kHz. The FEMTO3D Atlas addresses this gap by enabling high-speed, three-dimensional voltage imaging. Equipped with the real-time motion correction module - the 3D Real-Time Motion Correction - it achieves rapid imaging without motion artifacts and ensures high signal-to-noise ratio (SNR) for precise voltage imaging.

Features

Key features of Voltage Imaging

Indicators

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In Vivo Voltage Imaging

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In Vitro Voltage Imaging

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Samples

Single spikes, captured in vivo

Left
Right
In vitro JEDI-2P measurement combined with uncaging

In vitro JEDI-2P measurement combined with uncaging

In vivo drosophila imaging

In vivo drosophila imaging

3D voltage recording

3D voltage recording

Interviews & Webinars

The methods, explained by the people who use them

interview

An interview with Tristan Geiller: Shining a new light on memory formation

webinar

Tune in to the brain - 3D acousto-optic technology in multiphoton microscopy

interview

Interview with neuroscience researcher, Christopher Makinson, PHD.

Every Atlas ships with the team behind it
Service & support

Every Atlas ships with the team behind it

Installation, training, and ongoing support are handled directly by Femtonics engineers, not a distributor. From first light to advanced experiments, the people who built the system are the ones helping you run it.