An ambitious research collab aims to use 3-photon imaging, with a penetration depth three times than that of 2-photon techniques, to fulfill unmet clinical needs in cancer diagnostics – and Femtonics is a proud partner!

AMPLITUDE is propelled by a multidisciplinary team of European scientists, motivated by recent breakthroughs in multi-photon imaging. Such a breakthrough is three-photon imaging, which enables higher molecular imaging contrast and increased sensitivity of metabolic conditions, making its use favorable in cancer detection systems. However, there is currently a lack of suitable laser sources addressing this need. In the framework of AMPLITUDE, we are developing such new fiber laser sources and an innovative multi-modal microscopy and endoscopy platform, which will be able to achieve earlier diagnosis and improved monitoring of bladder cancer. Our FEMTOSmart Dual is the chosen platform for the implementation of ​preclinical multimodal tissue imaging, owing to its broad wavelength range and superior quality, customizable optical system. When this ability is combined with Raman and fluorescence imaging, the device will be able to achieve yet unseen specificity and sensitivity transformed in a microscope system, offering breakthrough diagnostics and therapy-monitoring possibilities.

Read the informative summary about the tech in development published in BioPhotonics here!