Blood Flow Imaging

Abnormal hemodynamics are implicated in disorders such as stroke and Alzheimer’s disease, yet understanding these links requires precise tools to measure blood flow in vivo in 3D.

About Blood Flow Imaging

Following blood flow deep in the living tissue - Abnormalities in hemodynamics are linked to various disease states, such as stroke, Alzheimer’s, etc., however, to better understand these associations, more precise optical techniques are needed for interrogating blood flow velocity in vivo in 3D. Acousto-optic (AO) multiphoton microscopy is a superior technique to perform blood flow tracking at the cellular level, at a high spatiotemporal resolution deep in the living 3D tissue. The unique scanning modes of the FEMTO3D Atlas allow you to record continuously along intricate 3D patterns, and its extensions make it possible to follow multiple parameters at the same time, like blood flow and cellular activity. These applications can be useful in various fields, such as neuroscience, immunology, dermatology, oncology and more.

Features

Key features of Blood Flow Imaging

Integrated 3D Blood Flow Platform

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3D Blood Flow Velocity Measurement

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Large-Scale 3D Vessel Tracking

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Simultaneous Blood Flow & Neural Activity

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Samples

Blood Flow Imaging samples

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In vivo imaging of blood flow in zebrafish eye. RED: tdTomato labelled blood cells. GREEN: GCaMP6 labelled neurons

Second Harmonic Generation imaging using label-free 2P microscopy

Second Harmonic Generation imaging using label-free 2P microscopy

Bloodstream measurement in 3D

Bloodstream measurement in 3D

Toxoplasma in mouse brain – in vivo - Migration of the infected cells in the blood capillars

Z-stack of cortical reconstruction