GRIN-lens Imaging
GRIN-lens Imaging with FEMTO3D Atlas enables fast, high-resolution 3D monitoring of neural activity in deep brain regions during behavior, with access to depths of up to 8 mm.
About GRIN lens imaging
GRIN (Gradient Refractive Index) lens imaging enables optical access to deep brain regions by inserting a gradient lens that focuses light below the cortical surface. FEMTO3D Atlas microscopes integrate acousto-optic scanning with GRIN lenses to achieve fast (up to 100 kHz) 3D in vivo imaging through the implanted lens, even during behavior, without requiring further lens movement. This method allows stable, high-resolution observation of neural activity within volumes of ~200 × 200 × 230 µm, reaching depths of up to 8000 µm below the surface. In addition, GRIN lens imaging minimizes photodamage, preserving tissue integrity while providing clear visualization of deep brain structures.
GRIN-lens Imaging samples
Hippocampal measurement
Advance your research with GRIN-lens Imaging
Talk to an application specialist about your research, or book a demo at one of our facilities.