3D Real-Time Motion Correction

3D Real-Time Motion Correction

Femtonics 3D-RTMC provides ultra-fast, real-time 3D motion correction for in vivo two-photon imaging, minimizing motion artifacts during neural recordings in all spatial directions.

Award winning 3D Real-Time Motion Correction

Femtonics has won the Innovation Award at the 32nd Hungarian Innovation Grand Award competition with the “Femtonics 3D-RTMC – 3D Real-Time Motion Correction“.

The award was presented by the Hungarian Intellectual Property Office during the ceremony held at the Parliament House. We would like to thank all our colleagues involved for their dedicated work, and thank you for the recognition!

About 3D Real-Time Motion Correction

The 3D real-time motion correction can compensate the visceral and intended movements of the model animal on a scale of a few hundred microseconds, enabling high sampling rate (up to 90 kHz) even for voltage sensor measurements. Residual motion during measurement is below 1 micrometer, so the recording will be virtually stable for any scanning modes.

Neuroscience relies more heavily on in vivo measurements of neuronal activity to study cognition, memory, CNS diseases, behaviour, neurochemistry, and many other aspects of the field. One of the bottlenecks of in vivo functional measurements is motion artifacts caused by the movement of the animal, respiration, circulation, or any of the numerous other sources. Here we offer a real-time solution for in vivo motion correction which eliminates artifacts caused by heartbeat, breathing or physical activity at over 100 kHz speed allowing calcium and voltage imaging from spines, dendrites, axons and somata with high resolution.

Key advantages

Advantages of 3D-RTMC technology

Acousto-optic based

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Useful for In Vivo measurements

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Real-time

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Reaction time

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Scanning modes

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